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SCIENCE & INNOVATION

PUBLICATIONS

Representative publications related to microbiota, biomarkers and screening guidelines of CRC...

Prospective colonoscopic study to investigate the risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas. Gut.

Siew C NG, …, Francis KL CHAN.

2020 Feb;69(2):304-310. (IF2018: 17.943)

Southern Chinese populations harbour non-nucleatum Fusobacteria possessing homologues of the colorectal cancer-associated FadA virulence factor. Gut.

Yeoh YK, …, Siew C NG, Sung JJY, Francis KL CHAN, Chan PKS.

2020 Feb 12. pii: gutjnl-2019-319635. doi: 10.1136/gutjnl-2019-319635. [Epub ahead of print] (IF2018: 17.943)

A Novel Fecal Lachnoclostridium Marker for the Non-Invasive Diagnosis of Colorectal Adenoma and Cancer. Gut.

Liang JQ, …, Siew C NG, Francis KL CHAN, et al.

2019 Sep 12 DOI 10.1136/gutjnl-2019-318532. (IF2018: 17.943)

Metagenomic analysis of fecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer. Gut.

Yu J, …, Siew C NG, Francis KL CHAN, et al.

2017 Jan;66(1):70-78. doi: 10.1136/gutjnl-2015-309800. Epub 2015 Sep 25. (IF2018: 17.943)

Fecal Bacteria Act as Novel Biomarkers for Non-Invasive Diagnosis of Colorectal Cancer. Clin Cancer Res.

Liang JQ, …, Siew C NG, …, Francis KL CHAN, et al.

2017 Apr 15;23(8):2061-2070. (IF2018: 8.911)

Peptostreptococcus anaerobius promotes colorectal carcinogenesis and modulates tumour immunity. Nat Microbiol. 

Long X, …, Francis KL CHAN, et al.

2019 Dec;4(12):2319-2330. (IF2018: 14.3)

Enteric fungal microbiota dysbiosis and ecological alterations in colorectal cancer. Gut.

Coker OO, Nakatsu G, Dai RZ, Wu WKK, Wong SH, Siew C NG, Francis KL CHAN, 

2019 Apr;68(4):654-662. doi: 10.1136/gutjnl-2018-317178. Epub 2018 Nov 24. (IF2018: 17.943)

Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer. Gastroenterology. 

Kwong TNY, …, Francis KL CHAN, Siew C NG, et al.

2018 Aug;155(2):383-390.e8. doi: 10.1053/j.gastro.2018.04.028. Epub 2018 May 3. (IF2018: 19.233)

Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes. Gastroenterology. 

Nakatsu G, …, Siew C NG, Francis KL CHAN, et al.

2018 Aug;155(2):529-541.e5. doi: 10.1053/j.gastro.2018.04.018. Epub 2018 Apr 22. (IF2018: 19.233)

​​Multi-cohort analysis of colorectal cancer metagenome identified altered bacteria across populations and universal bacterial markers. Microbiome. 

Dai Z, …, Francis KL CHAN, et al.

2018 Apr 11;6(1):70. doi: 10.1186/s40168-018-0451-2. (IF2018: 10.465)

Gavage of Fecal Samples From Patients With Colorectal Cancer Promotes Intestinal Carcinogenesis in Germ-Free and Conventional Mice. Gastroenterology.

Wong SH, …, Francis KL CHAN, et al.

2017 Dec;153(6):1621-1633.e6. doi: 10.1053/j.gastro.2017.08.022. Epub 2017 Aug 18. (IF2018: 19.233)

Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut.

Wong SH, …, Francis KL CHAN, Siew C NG, et al.

2017 Aug;66(8):1441-1448. doi: 10.1136/gutjnl-2016-312766. Epub 2016 Oct 24. (IF2018: 17.943)

Peptostreptococcus anaerobius Induces Intracellular Cholesterol Biosynthesis in Colon Cells to Induce Proliferation and Causes Dysplasia in Mice. Gastroenterology. 

Tsoi H, …, Siew C NG, Francis KL CHAN, et al

2017 May;152(6):1419-1433.e5. (IF2018: 19.233)

Risk of Colorectal Neoplasia in Individuals With Self-Reported Family History: A Prospective Colonoscopy Study from 16 Asia-Pacific Regions. Am J Gastroenterol. 

Wong MC, …, Siew C NG, Francis KL CHAN, Sung JJ.

2016 Nov;111(11):1621-1629. doi: 10.1038/ajg.2016.52. Epub 2016 Mar 15. (IF2018: 10.241)

Risk of Advanced Adenomas in Siblings of Individuals With Advanced Adenomas: A Cross-Sectional Study. Gastroenterology. 

Siew C NG, …, Francis KL CHAN, et al.

2016 Mar;150(3):608-16; quiz e16-7. doi: 10.1053/j.gastro.2015.11.003. (IF2018: 19.233)

Diagnostic Accuracy of a Qualitative Fecal Immunochemical Test Varies With Location of Neoplasia But Not Number of Specimens. Clin Gastroenterol Hepatol. 

Wong MC, …, Siew C NG, Francis KL CHAN, et al.

2015 Aug;13(8):1472-9. (IF2018: 7.958)

Association between serrated polyps and the risk of synchronous advanced colorectal neoplasia in average-risk individuals. Aliment Pharmacol Ther. 

Siew C NG, …, Francis KL CHAN, et al.

2015 Jan;41(1):108-15. doi: 10.1111/apt.13003. Epub 2014 Oct 22. (IF2018: 7.731)

An updated Asia Pacific Consensus Recommendations on colorectal cancer screening. Gut.

Sung JJ, Siew C NG, Francis KL CHAN, et al; Asia Pacific Working Group.

2015 Jan;64(1):121-32. (IF2018: 17.943)

A validated tool to predict colorectal neoplasia and inform screening choice for asymptomatic subjects. Gut.

Wong MC, …, Francis KL CHAN, et al.

2014 Jul;63(7):1130-6. (IF2018: 17.943)

Diagnostic accuracy of faecal immunochemical test for screening individuals with a family history of colorectal cancer. Aliment Pharmacol Ther. 

Siew C NG, …, Francis KL CHAN, et al.

2013 Oct;38(7):835-41. (IF2018: 7.731)

Increased risk of advanced neoplasms among asymptomatic siblings of patients with colorectal cancer. Gastroenterology. 

Siew C NG, …, Francis KL CHAN, et al.

2013 Mar;144(3):544-50. (IF2018: 19.233)

A comparison of the acceptance of immunochemical faecal occult blood test and colonoscopy in colorectal cancer screening: a prospective study among Chinese. Aliment Pharmacol Ther.

Wong MC, Tsoi KK, Ng SS, …, Francis KL CHAN, et al.

2010 Jul;32(1):74-82 (IF2018: 7.731)

Asia Pacific consensus recommendations for colorectal cancer screening. Gut.

Sung JJ, Lau JY, …, Francis KL CHAN; Asia Pacific Working Group on Colorectal Cancer. 

2008 Aug;57(8):1166-76. doi: 10.1136/gut.2007.146316. (IF2018: 17.943)

Obstacles to colorectal cancer screening in Chinese: a study based on the health belief model. Am J Gastroenterol. 

Sung JJ, Choi SY, Francis KL CHAN, et al.

2008 Apr;103(4):974-81. Epub 2007 Nov 28. (IF2018: 10.241)

Screening for colorectal cancer in Chinese: comparison of fecal occult blood test, flexible sigmoidoscopy, and colonoscopy. Gastroenterology.

Sung JJ, Francis KL CHAN, et al.

2003 Mar;124(3):608-14. (IF2018: 19.233)

Representative publications related to immunity:

Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19. Gut 2020.

Zuo T, Liu Q, Zhang F, et al.

 

Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge. Gastroenterology 2020.

Zuo T, Zhan H, Zhang F, et al.

Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization. Gastroenterology 2020; 159(3): 944-55.e8.

Zuo T, Zhang F, Lui GCY, et al.

 

Probiotics and COVID-19: one size does not fit all. Lancet Gastroenterol Hepatol 2020; 5(7): 644-5.

Ng SC, Tilg H. COVID-19, and the gastrointestinal tract: more than meets the eye. Gut 2020; 69(6): 973-4.

Mak JWY, Chan FKL, Ng SC.