FKL Chan, MCS Wong, AT Chan, JE East, HM Chiu, GK Makharia, D Weller, CJ Ooi, J Limsrivilai, Y Saito, DV Hang, JD Emery, D Makmun, KC Wu, RAR Ali, and SC Ng, Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia. Gut, 04, 2023: p. 15. DOI: https://doi.org/10.1136/gutjnl-2023-329429
JQ Liang, Y Zeng, EYT Lau, Y Sun, Y Huang, T Zhou, Z Xu, J Yu, SC Ng, and FKL Chan, A Probiotic Formula for Modulation of Colorectal Cancer Risk via Reducing CRC-Associated Bacteria. Cells, 04, 2023. 12(9). DOI: https://doi.org/10.3390/cells12091244
M Iwatate, D Hirata, CPD Francisco, JT Co, JS Byeon, N Joshi, R Banerjee, DT Quach, TT Aye, HM Chiu, LH Louis, SC Ng, TL Ang, S Khomvilai, XB Li, SH Ho, W Sano, S Hattori, M Fujita, Y Murakami, M Shimatani, Y Kodama, and Y Sano, Efficacy of international web-based educational intervention in the detection of high-risk flat and depressed colorectal lesions higher (CATCH project) with a video: A randomized trial. Digestive Endoscopy, 02, 2022. DOI: https://doi.org/10.1111/den.14244
C Foppa, SC Ng, M Montorsi, and A Spinelli, Anastomotic leak in colorectal cancer patients: New insights and perspectives. European Journal of Oncology, 02, 2020. DOI: https://doi.org/10.1016/j.ejso.2020.02.027
SC Ng, MH Kyaw, BY Suen, YK Tse, MCS Wong, AJ Hui, HY Tak, JYW Lau, JJY Sung, and FKL Chan, Prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas. Gut, 04, 2019. DOI: https://doi.org/10.1136/gutjnl-2018-318117
HW Hirai, JYL Ching, JCY Wu, JJY Sung, FKL Chan, and SC Ng, Risk factors for advanced colorectal neoplasms in the proximal colon in 6218 subjects undergoing complete colonoscopy. Journal of Gastroenterology and Hepatology, 01, 2018. 34(1): p. 113-119. DOI: https://doi.org/10.1111/jgh.14357
MCS Wong, JYL Ching, HM Chiu, KC Wu, R Rerknimitr, J Li, DC Wu, KL Goh, T Matsuda, HS Kim, R Leong, KG Yeoh, VH Chong, JD Sollano, F Ahmed, J Menon, SC Ng, JCY Wu, FKL Chan, and JJY Sung, Risk of Colorectal Neoplasia in Individuals with Self-Reported Family History: A Prospective Colonoscopy Study from 16 Asia-Pacific Regions. American Journal of Gastroenterology, 11, 2016. 111(11): p. 1621-1629. DOI: https://doi.org/10.1038/ajg.2016.52
MC Wong, JY Ching, VC Chan, RS Tang, AK Luk, TY Lam, SS Wong, SC Ng, SS Ng, JC Wu, FK Chan, and JJ Sung, Validation of a risk prediction score for proximal neoplasia in colorectal cancer screening: a prospective colonoscopy study. Scientific Reports, 08, 2016. 6: p. 20396. DOI: https://doi.org/10.1038/srep20396
HW Hirai, KKF Tsoi, JYC Chan, SH Wong, JYL Ching, MCS Wong, JCY Wu, FKL Chan, JJY Sung, and SC Ng, Systematic review with meta-analysis: Faecal occult blood tests show lower colorectal cancer detection rates in the proximal colon in colonoscopy-verified diagnostic studies. Alimentary Pharmacology and Therapeutics, 04, 2016. 43(7): p. 755-764. DOI: https://doi.org/10.1111/apt.13556
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SH Wong, SC Ng, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Colorectal cancer screening based on age and gender: A cost-effectiveness analysis. Medicine, 03, 2016. 95(10): p. e2739. DOI: https://doi.org/10.1097/MD.0000000000002739
MC Wong, JY Ching, S Ng, TY Lam, AK Luk, SH Wong, SC Ng, SS Ng, JC Wu, FK Chan, and JJ Sung, The discriminatory capability of existing scores to predict advanced colorectal neoplasia: a prospective colonoscopy study of 5,899 screening participants. Scientific Reports, 02, 2016. 6: p. 20080. DOI: https://doi.org/10.1038/srep20080
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SH Wong, SC Ng, VWS Wong, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Screening strategies for colorectal cancer among patients with nonalcoholic fatty liver disease and family history. International Journal of Cancer, 02, 2016. 138: p. 576-583. DOI: https://doi.org/10.1002/ijc.29809
MCS Wong, SH Wong, SC Ng, JCY Wu, FKL Chan, and JJY Sung, Targeted screening for colorectal cancer in high-risk individuals. Best Practice & Research Clinical Gastroenterology, 12, 2015. 29(6): p. 941-951. DOI: https://doi.org/10.1016/j.bpg.2015.09.006
Q Gao, KKF Tsoi, HW Hirai, MCS Wong, FKL Chan, JCY Wu, JYW Lau, JJY Sung, and SC Ng, Serrated polyps and the risk of synchronous colorectal advanced neoplasia: A systematic review and meta-analysis. American Journal of Gastroenterology, 04, 2015. 110(4): p. 501-509. DOI: https://doi.org/10.1038/ajg.2015.49
SC Ng, JYL Ching, VCW Chan, MCS Wong, R Tang, S Wong, AKC Luk, TYT Lam, Q Gao, AWH Chan, JCY Wu, FKL Chan, JYW Lau, and JJY Sung, Association between serrated polyps and the risk of synchronous advanced colorectal neoplasia in average-risk individuals. Alimentary Pharmacology and Therapeutics, 01, 2015. 41(1): p. 108-115. DOI: https://doi.org/10.1111/apt.13003
JJY Sung, SC Ng, FKL Chan, HM Chiu, HS Kim, T Matsuda, SSM Ng, JYW Lau, S Zheng, S Adler, N Reddy, KG Yeoh, KKF Tsoi, JYL Ching, EJ Kuipers, L Rabeneck, GP Young, RJ Steele, D Lieberman, and KL Goh, An updated Asia Pacific Consensus Recommendations on colorectal cancer screening. Gut, 01, 2015. 64(1): p. 121-132. DOI: https://doi.org/10.1136/gutjnl-2013-306503
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SH Wong, SC Ng, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Identification of subjects at risk of proximal advanced neoplasia for colorectal cancer screening. European Journal of Cancer, 01, 2015. 51: p. 37-44. DOI: https://doi.org/10.1016/j.ejca.2014.10.003
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SC Ng, SSM Ng, and JJY Sung, Informed choice vs. no choice in colorectal cancer screening tests: A prospective cohort study in real-life screening practice. American Journal of Gastroenterology, 07, 2014. 109(7): p. 1072-1079. DOI: https://doi.org/10.1038/ajg.2014.136
CW Wu, SC Ng, Y Dong, L Tian, SSM Ng, WW Leung, WT Law, TO Yau, FKL Chan, JJY Sung, and J Yu, Identification of microrna-135b in stool as a potential noninvasive biomarker for colorectal cancer and adenoma. Clinical Cancer Research, 06, 2014. 20: p. 2994-3002. DOI: https://doi.org/10.1158/1078-0432.CCR-13-1750
SC Ng, JYL Ching, V Chan, MCS Wong, BY Suen, HW Hirai, TYT Lam, WL J.Y, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Diagnostic accuracy of faecal immunochemical test for screening individuals with a family history of colorectal cancer. Alimentary Pharmacology and Therapeutics, 10, 2013. 38(7): p. 835-841. DOI: https://doi.org/10.1111/apt.12446
SC Ng, JYW Lau, FKL Chan, BY Suen, WK Leung, YK Tse, SSM Ng, JFY Lee, KF To, JCY Wu, and JJY Sung, Increased risk of advanced neoplasms among asymptomatic siblings of patients with colorectal cancer. Gastroenterology, 03, 2013. 144(3): p. 544-550. DOI: https://doi.org/10.1053/j.gastro.2012.11.011
SC Ng and SH Wong, Colorectal cancer screening in Asia. British Medical Bulletin, 03, 2013. 105: p. 29-42. DOI: https://doi.org/10.1093/bmb/lds040
CW Wu, SS Ng, YJ Dong, SC Ng, WW Leung, CW Lee, YN Wong, FK Chan, J Yu, and JJ Sung, Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps. Gut, 05, 2012. 61(5): p. 739-45. DOI: https://doi.org/10.1136/gut.2011.239236
Y Wan, T Zuo, Z Xu, F Zhang, H Zhan, D Chan, TF Leung, YK Yeoh, FKL Chan, R Chan, and SC Ng, Underdevelopment of the gut microbiota and bacteria species as non-invasive markers of prediction in children with autism spectrum disorder. Gut, 07, 2021. DOI: https://doi.org/10.1136/gutjnl-2020-324015
JY Zheng, QR Sun, JW Zhang, and SC Ng, The role of gut microbiome in inflammatory bowel disease diagnosis and prognosis. United European Gastroenterology Journal, 12, 2022. 10(10): p. 1091-1102. DOI: https://doi.org/10.1002/ueg2.12338
JWY Mak, S Yang, A Stanley, XQ Lin, M Morrison, JYL Ching, JK Niu, AL Wilson-O'Brien, R Feng, W Tang, AL Hamilton, L Or, GL Trakman, WYY Lin, JJY Sung, MH Chen, YL Mao, MA Kamm, and SC Ng, Childhood antibiotics as a risk factor for Crohn's disease: The ENIGMA International Cohort Study. Jgh Open, 06, 2022. 6(6): p. 369-377. DOI: https://doi.org/10.1002/jgh3.12755
SM Lin, LH Lau, N Chanchlani, NA Kennedy, and SC Ng, Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic. Gut, 04, 2022: p. 14. DOI: https://doi.org/10.1136/gutjnl-2021-326784
X Zhilu, D Xiangqian, Y Keli, C Caroline, Z Jingwan, L Yu, Z Tao, CL Cheung, S Yang, Z Fengrui, CF Kl, SJ Jy, Y Jun, B Anthony, B Nicolas, C Jean-Frederic, WS Hei, M Yinglei, and CN Siew, Association of Adherent-invasive Escherichia coli with severe Gut Mucosal dysbiosis in Hong Kong Chinese population with Crohn's disease. Gut Microbes, 11, 2021. 13(1). DOI: https://doi.org/10.1080/19490976.2021.1994833
J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh, A Hamilton, OB AW, JYL Ching, H Wei, K Yang, Z Xu, SH Wong, JWY Mak, JJY Sung, M Morrison, J Yu, MA Kamm, and SC Ng, Elucidation of Proteus mirabilis as a Key Bacterium in Crohn's Disease Inflammation. Gastroenterology, 01, 2021. 160(1): p. 317-330.e11. DOI: https://doi.org/10.1053/j.gastro.2020.09.036
JWY Mak, MT Weng, SC Wei, and SC Ng, Zero COVID-19 infection in inflammatory bowel disease patients: Findings from population-based inflammatory bowel disease registries in Hong Kong and Taiwan. Journal of Gastroenterology and Hepatology, 06, 2020. DOI: https://doi.org/10.1111/jgh.15164
JHS You, X Jiang, WH Lee, PKS Chan, and SC Ng, Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection in patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology, 02, 2020. DOI: https://doi.org/10.1111/jgh.15002
S Lam, T Zuo, M Ho, FKL Chan, PKS Chan, and SC Ng, Review article: fungal alterations in inflammatory bowel diseases. Alimentary Pharmacology and Therapeutics, 12, 2019. 50(11-12): p. 1159-1171. DOI: https://doi.org/10.1111/apt.15523
T Zuo, XJ Lu, Y Zhang, CP Cheung, S Lam, F Zhang, W Tang, JYL Ching, R Zhao, PKS Chan, JJY Sung, J Yu, FKL Chan, Q Cao, JQ Sheng, and SC Ng, Gut mucosal virome alterations in ulcerative colitis. Gut, 07, 2019. 68(7): p. 1169-1179. DOI: https://doi.org/10.1136/gutjnl-2018-318131
T Zuo and SC Ng, Authors response: giant oversights in the human gut virome. Gut, 07, 2019. DOI: https://doi.org/10.1136/gutjnl-2019-319357
T Zuo and SC Ng, The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease. Frontiers in Microbiology, 09, 2018. 9: p. 2247. DOI: https://doi.org/10.3389/fmicb.2018.02247
T Zuo, MA Kamm, JF Colombel, and SC Ng, Urbanization and the gut microbiota in health and inflammatory bowel disease. Nature Reviews Gastroenterology & Hepatology, 07, 2018. 15(7): p. 440-452. DOI: https://doi.org/10.1038/s41575-018-0003-z
SC Ng, JL Benjamin, NE McCarthy, CRH Hedin, A Koutsoumpas, S Plamondon, CL Price, AL Hart, MA Kamm, A Forbes, SC Knight, JO Lindsay, K Whelan, and AJ Stagg, Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflammatory Bowel Diseases, 10, 2011. 17(10): p. 2027-2037. DOI: https://doi.org/10.1002/ibd.21590
SC Ng, MA Kamm, J Stagg, and SC Knight, Intestinal Dendritic Cells: Their Role in Bacterial Recognition, Lymphocyte Homing, and Intestinal Inflammation. Inflammatory Bowel Diseases, 10, 2010. 16(10): p. 1787-1807. DOI: https://doi.org/10.1002/ibd.21247
SC Ng, S Plamondon, MA Kamm, AL Hart, HO Al-Hassi, T Guenther, AJ Stagg, and SC Knight, Immunosuppressive effects via human intestinal dendritic cells of probiotic bacteria and steroids in the treatment of acute ulcerative colitis. Inflammatory Bowel Diseases, 08, 2010. 16(8): p. 1286-98. DOI: https://doi.org/10.1002/ibd.21222
SC Ng, AL Hart, MA Kamm, AJ Stagg, and SC Knight, Mechanisms of action of probiotics: Recent advances. Inflammatory Bowel Diseases, 02, 2009. 15(2): p. 300-310. DOI: https://doi.org/10.1002/ibd.20602
YK Yau, LH Shing Lau, RN Shun Lui, SH Wong, CL Guo, JW Yan Mak, JY Ling Ching, M Ip, MA Kamm, DT Rubin, PK Sheung Chan, FK Leung Chan, and SC Ng, Long-Term Safety Outcomes of Fecal Microbiota Transplantation: Real-World Data Over 8 Years From the Hong Kong FMT Registry. Clinical Gastroenterology and Hepatology, Sep 19, 2023. DOI: https://doi.org/10.1016/j.cgh.2023.09.001
YK Yau, Q Su, Z Xu, W Tang, JYL Ching, JWY Mak, CP Cheung, M Fung, M Ip, PKS Chan, JCY Wu, FKL Chan, and SC Ng, Randomised clinical trial: Faecal microbiota transplantation for irritable bowel syndrome with diarrhoea. Alimentary Pharmacology & Therapeutics, Oct, 2023. 58(8): p. 795-804. DOI: https://doi.org/10.1111/apt.17703
Q Liu, Z Xu, M Dai, Q Su, FK Leung Chan, and SC Ng, Faecal microbiota transplantations and the role of bacteriophages. Clinical Microbiology and Infection, 06, 2023. 29(6): p. 689-694. DOI: https://doi.org/10.1016/j.cmi.2022.11.012
ZL Xu, JWY Mak, Y Lin, KL Yang, Q Liu, F Zhang, L Lau, WT Tang, JYL Ching, HM Tun, PL Chan, FKL Chan, and SC Ng, Mixed-donor faecal microbiota transplantation was associated with increased butyrate-producing bacteria for obesity. Gut, 03, 2023. DOI: https://doi.org/10.1136/gutjnl-2022-328993
Q Liu, T Zuo, WQ Lu, Y Yeoh, Q Su, ZL Xu, N Tang, KL Yang, F Zhang, LHS Lau, RNS Lui, ML Chin, R Wong, CP Cheung, WY Zhu, P Chan, RC Chan, GC Lui, and SC Ng, Longitudinal Evaluation of Gut Bacteriomes and Viromes after Fecal Microbiota Transplantation for Eradication of Carbapenem-Resistant Enterobacteriaceae. Msystems, 06, 2022: p. 16. DOI: https://doi.org/10.1128/msystems.01510-21
YK Yau, WYJ Mak, NSR Lui, WYR Ng, CYK Cheung, YLA Li, YLJ Ching, ML Chin, HSL Lau, KLF Chan, KSP Chan, and SC Ng, High prevalence of extended-spectrum beta-lactamase organisms and the COVID-19 pandemic impact on donor recruitment for fecal microbiota transplantation in Hong Kong. United European Gastroenterology Journal, 11, 2021. 9(9): p. 1027-1038. DOI: https://doi.org/10.1002/ueg2.12160
F Zhang, T Zuo, YK Yeoh, FWT Cheng, Q Liu, W Tang, KCY Cheung, KL Yang, CP Cheung, CC Mo, MM Hui, FKL Chan, CK Li, PKS Chan, and SC Ng, Longitudinal dynamics of gut bacteriome, mycobiome and virome after fecal microbiota transplantation in graft-versus-host disease. Nature Communications, 01, 2021. 12(1): p. 11. DOI: https://doi.org/10.1038/s41467-020-20240-x
JHS You, X Jiang, WH Lee, PKS Chan, and SC Ng, Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection in patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology, 02, 2020. DOI: https://doi.org/10.1111/jgh.15002
SC Ng, MA Kamm, YK Yeoh, PKS Chan, T Zuo, W Tang, A Sood, A Andoh, N Ohmiya, Y Zhou, CJ Ooi, V Mahachai, CY Wu, F Zhang, K Sugano, and FKL Chan, Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE). Gut, 01, 2020. 69(1): p. 83-91. DOI: https://doi.org/10.1136/gutjnl-2019-319407
RN Lui, SH Wong, LHS Lau, TT Chan, KCY Cheung, A Li, ML Chin, W Tang, JYL Ching, KLY Lam, PKS Chan, JCY Wu, JJY Sung, FKL Chan, and SC Ng, Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong. Hong Kong Medical Journal, 06, 2019. 25(3): p. 178-182. DOI: https://doi.org/10.12809/hkmj197855
CY Lai, J Sung, F Cheng, W Tang, SH Wong, PKS Chan, MA Kamm, JJY Sung, G Kaplan, FKL Chan, and SC Ng, Systematic review with meta-analysis: review of donor features, procedures and outcomes in 168 clinical studies of faecal microbiota transplantation. Alimentary Pharmacology and Therapeutics, 02, 2019. 49(4): p. 354-363. DOI: https://doi.org/10.1111/apt.15116
T Zuo, SH Wong, CP Cheung, K Lam, R Lui, K Cheung, F Zhang, W Tang, JYL Ching, JCY Wu, PKS Chan, JJY Sung, J Yu, FKL Chan, and SC Ng, Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection. Nature Communications, 09, 2018. 9(1): p. 3663. DOI: https://doi.org/10.1038/s41467-018-06103-6
T Zuo, SH Wong, K Lam, R Lui, K Cheung, W Tang, JYL Ching, PKS Chan, MCW Chan, JCY Wu, FKL Chan, J Yu, JJY Sung, and SC Ng, Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome. Gut, 04, 2017. 67(4): p. 634-643. DOI: https://doi.org/10.1136/gutjnl-2017-313952
Y Peng, L Zhang, CKP Mok, JYL Ching, S Zhao, MKL Wong, J Zhu, C Chen, S Wang, S Yan, B Qin, Y Liu, X Zhang, CP Cheung, PK Cheong, KL Ip, ACH Fung, KKY Wong, DSC Hui, FKL Chan, SC Ng, and HM Tun, Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines. Signal Transduction and Targeted Therapy, Sep 25, 2023. 8(1): p. 373. DOI: https://doi.org/10.1038/s41392-023-01629-8
RI Lau, Q Su, ISF Lau, JYL Ching, MCS Wong, LHS Lau, HM Tun, CKP Mok, SWH Chau, YK Tse, CP Cheung, MKT Li, GTY Yeung, PK Cheong, FKL Chan, and SC Ng, A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial. Lancet Infectious Diseases, 12, 2023(Published Online). DOI: https://doi.org/10.1016/s1473-3099(23)00685-0
MCS Wong, L Zhang, JYL Ching, JWY Mak, JJ Huang, SL Wang, CKP Mok, AG Wong, OL Chiu, YT Fung, PK Cheong, HM Tun, SC Ng, and FKL Chan, Effects of Gut Microbiome Modulation on Reducing Adverse Health Outcomes among Elderly and Diabetes Patients during the COVID-19 Pandemic: A Randomised, Double-Blind, Placebo-Controlled Trial (IMPACT Study). Nutrients, 04, 2023. 15(8). DOI: https://doi.org/10.3390/nu15081982
MCS Wong, JJ Huang, YY Wong, GLH Wong, TCF Yip, RNY Chan, SWH Chau, SC Ng, YK Wing, and FKL Chan, Epidemiology, Symptomatology, and Risk Factors for Long COVID Symptoms: Population-Based, Multicenter Study. Jmir Public Health and Surveillance, 03, 2023. 9: p. 15. DOI: https://doi.org/10.2196/42315
Q Su, Q Liu, L Zhang, ZL Xu, CY Liu, WQ Lu, JYL Ching, A Li, JWY Mak, GCY Lui, SSS Ng, KM Chow, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients. Gut Microbes, 12, 2022. 14(1): p. 16. DOI: https://doi.org/10.1080/19490976.2022.2128603
Q Liu, Q Su, F Zhang, HM Tun, JWY Mak, GCY Lui, SSS Ng, JYL Ching, A Li, WQ Lu, CY Liu, CP Cheung, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34535-8
Q Su, Q Liu, RI Lau, JW Zhang, ZL Xu, YK Yeoh, TWH Leung, W Tang, L Zhang, JQY Liang, YK Yau, JY Zheng, CY Liu, MJ Zhang, CP Cheung, JYL Ching, HM Tun, J Yu, FKL Chan, and SC Ng, Faecal microbiome-based machine learning for multi-class disease diagnosis. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34405-3
RI Lau, F Zhang, Q Liu, Q Su, FKL Chan, and SC Ng, Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications. Nature Reviews Gastroenterology & Hepatology, 10, 2022: p. 15. DOI: https://doi.org/10.1038/s41575-022-00698-4
Q Su, RI Lau, Q Liu, FKL Chan, and SC Ng, Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance. Gut, 08, 2022: p. 2. DOI: https://doi.org/10.1136/gutjnl-2022-328319
SM Lin, LH Lau, N Chanchlani, NA Kennedy, and SC Ng, Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic. Gut, 04, 2022: p. 14. DOI: https://doi.org/10.1136/gutjnl-2021-326784
Q Liu, JWY Mak, Q Su, YK Yeoh, GC Lui, SSS Ng, F Zhang, AYL Li, W Lu, DS Hui, PK Chan, FKL Chan, and SC Ng, Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome. Gut, 03, 2022. 71(3): p. 544-552. DOI: https://doi.org/10.1136/gutjnl-2021-325989
L Zhang, Z Xu, JWY Mak, KM Chow, G Lui, TCM Li, CK Wong, PKS Chan, JYL Ching, Y Fujiwara, FKL Chan, and SC Ng, Gut microbiota-derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID-19: An open-label pilot study. Journal of Gastroenterology and Hepatology, 03, 2022. (Online First). DOI: https://doi.org/10.1111/jgh.15796
SC Ng, Y Peng, L Zhang, CK Mok, S Zhao, A Li, JY Ching, Y Liu, S Yan, DLS Chan, J Zhu, C Chen, AC Fung, KK Wong, DS Hui, FK Chan, and HM Tun, Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events. Gut, 02, 2022. DOI: https://doi.org/10.1136/gutjnl-2021-326563
YK Yau, WYJ Mak, NSR Lui, WYR Ng, CYK Cheung, YLA Li, YLJ Ching, ML Chin, HSL Lau, KLF Chan, KSP Chan, and SC Ng, High prevalence of extended-spectrum beta-lactamase organisms and the COVID-19 pandemic impact on donor recruitment for fecal microbiota transplantation in Hong Kong. United European Gastroenterology Journal, 11, 2021. 9(9): p. 1027-1038. DOI: https://doi.org/10.1002/ueg2.12160
F Zhang, Y Wan, T Zuo, YK Yeoh, Q Liu, L Zhang, H Zhan, W Lu, W Xu, GCY Lui, AYL Li, CP Cheung, CK Wong, PKS Chan, FKL Chan, and SC Ng, Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19. Gastroenterology, 10, 2021. DOI: https://doi.org/10.1053/j.gastro.2021.10.013
MF Neurath, K Uberla, and SC Ng, Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19. Gut, 09, 2021. 70(9): p. 1605-1608. DOI: https://doi.org/10.1136/gutjnl-2021-324622
YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li, ACK Chung, CP Cheung, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, KM Chow, SSS Ng, TCM Li, RWY Ng, TCF Yip, GLH Wong, FKL Chan, CK Wong, PKS Chan, and SC Ng, Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19. Gut, 04, 2021. 70(4): p. 698-706. DOI: https://doi.org/10.1136/gutjnl-2020-323020
T Zuo, Q Liu, F Zhang, YK Yeoh, YT Wan, H Zhan, GCY Lui, ZG Chen, AYL Li, CP Cheung, N Chen, WQ Lv, RWY Ng, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity. Microbiome, 04, 2021. 9(1): p. 16. DOI: https://doi.org/10.1186/s40168-021-01008-x
JL Hu, L Zhang, W Lin, W Tang, FKL Chan, and SC Ng, Review article: Probiotics, prebiotics and dietary approaches during COVID-19 pandemic. Trends in Food Science & Technology, 02, 2021. 108: p. 187-196. DOI: https://doi.org/10.1016/j.tifs.2020.12.009
T Zuo, Q Liu, F Zhang, GCY Lui, EYK Tso, YK Yeoh, ZG Chen, SS Boon, FKL Chan, PKS Chan, and SC Ng, Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19. Gut, 02, 2021. 70(2): p. 276-284. DOI: https://doi.org/10.1136/gutjnl-2020-322294
SC Ng, JWY Mak, L Hitz, Y Chowers, CN Bernstein, and MS Silverberg, COVID-19 Pandemic: Which IBD Patients Need to Be Scoped-Who Gets Scoped Now, Who Can Wait, and how to Resume to Normal. Journal of Crohn's & Colitis, 10, 2020. 14(Supplement_3): p. S791-s797. DOI: https://doi.org/10.1093/ecco-jcc/jjaa128
JWY Mak, MT Weng, SC Wei, and SC Ng, Zero COVID-19 infection in inflammatory bowel disease patients: Findings from population-based inflammatory bowel disease registries in Hong Kong and Taiwan. Journal of Gastroenterology and Hepatology, 06, 2020. DOI: https://doi.org/10.1111/jgh.15164
SC Ng and H Tilg, COVID-19 and the gastrointestinal tract: more than meets the eye. Gut, 06, 2020. 69(6): p. 973-974. DOI: https://doi.org/10.1136/gutjnl-2020-321195
T Zuo, H Zhan, F Zhang, Q Liu, EYK Tso, GCY Lui, N Chen, A Li, W Lu, FKL Chan, PKS Chan, and SC Ng, Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge. Gastroenterology, 06, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.06.048
T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan, Y Wan, A Chung, CP Cheung, N Chen, CKC Lai, Z Chen, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization. Gastroenterology, 05, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.05.048
PWY Chiu, SC Ng, H Inoue, DN Reddy, E Ling Hu, JY Cho, LK Ho, DG Hewett, HM Chiu, R Rerknimitr, HP Wang, SH Ho, DW Seo, KL Goh, H Tajiri, S Kitano, and FKL Chan, Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements). Gut, 04, 2020. DOI: https://doi.org/10.1136/gutjnl-2020-321185
JWY Mak, FKL Chan, and SC Ng, Probiotics and COVID-19: one size does not fit all. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30122-9
SC Ng, FKL Chan, and PKS Chan, Screening FMT donors during the COVID-19 pandemic: a protocol for stool SARS-CoV-2 viral quantification. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30124-2
Y Peng, L Zhang, CKP Mok, JYL Ching, S Zhao, MKL Wong, J Zhu, C Chen, S Wang, S Yan, B Qin, Y Liu, X Zhang, CP Cheung, PK Cheong, KL Ip, ACH Fung, KKY Wong, DSC Hui, FKL Chan, SC Ng, and HM Tun, Baseline gut microbiota and metabolome predict durable immunogenicity to SARS-CoV-2 vaccines. Signal Transduction and Targeted Therapy, Sep 25, 2023. 8(1): p. 373. DOI: https://doi.org/10.1038/s41392-023-01629-8
RI Lau, Q Su, ISF Lau, JYL Ching, MCS Wong, LHS Lau, HM Tun, CKP Mok, SWH Chau, YK Tse, CP Cheung, MKT Li, GTY Yeung, PK Cheong, FKL Chan, and SC Ng, A synbiotic preparation (SIM01) for post-acute COVID-19 syndrome in Hong Kong (RECOVERY): a randomised, double-blind, placebo-controlled trial. Lancet Infectious Diseases, 12, 2023(Published Online). DOI: https://doi.org/10.1016/s1473-3099(23)00685-0
MCS Wong, L Zhang, JYL Ching, JWY Mak, JJ Huang, SL Wang, CKP Mok, AG Wong, OL Chiu, YT Fung, PK Cheong, HM Tun, SC Ng, and FKL Chan, Effects of Gut Microbiome Modulation on Reducing Adverse Health Outcomes among Elderly and Diabetes Patients during the COVID-19 Pandemic: A Randomised, Double-Blind, Placebo-Controlled Trial (IMPACT Study). Nutrients, 04, 2023. 15(8). DOI: https://doi.org/10.3390/nu15081982
MCS Wong, JJ Huang, YY Wong, GLH Wong, TCF Yip, RNY Chan, SWH Chau, SC Ng, YK Wing, and FKL Chan, Epidemiology, Symptomatology, and Risk Factors for Long COVID Symptoms: Population-Based, Multicenter Study. Jmir Public Health and Surveillance, 03, 2023. 9: p. 15. DOI: https://doi.org/10.2196/42315
Q Su, Q Liu, L Zhang, ZL Xu, CY Liu, WQ Lu, JYL Ching, A Li, JWY Mak, GCY Lui, SSS Ng, KM Chow, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients. Gut Microbes, 12, 2022. 14(1): p. 16. DOI: https://doi.org/10.1080/19490976.2022.2128603
Q Liu, Q Su, F Zhang, HM Tun, JWY Mak, GCY Lui, SSS Ng, JYL Ching, A Li, WQ Lu, CY Liu, CP Cheung, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34535-8
Q Su, Q Liu, RI Lau, JW Zhang, ZL Xu, YK Yeoh, TWH Leung, W Tang, L Zhang, JQY Liang, YK Yau, JY Zheng, CY Liu, MJ Zhang, CP Cheung, JYL Ching, HM Tun, J Yu, FKL Chan, and SC Ng, Faecal microbiome-based machine learning for multi-class disease diagnosis. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34405-3
RI Lau, F Zhang, Q Liu, Q Su, FKL Chan, and SC Ng, Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications. Nature Reviews Gastroenterology & Hepatology, 10, 2022: p. 15. DOI: https://doi.org/10.1038/s41575-022-00698-4
Q Su, RI Lau, Q Liu, FKL Chan, and SC Ng, Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance. Gut, 08, 2022: p. 2. DOI: https://doi.org/10.1136/gutjnl-2022-328319
SM Lin, LH Lau, N Chanchlani, NA Kennedy, and SC Ng, Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic. Gut, 04, 2022: p. 14. DOI: https://doi.org/10.1136/gutjnl-2021-326784
Q Liu, JWY Mak, Q Su, YK Yeoh, GC Lui, SSS Ng, F Zhang, AYL Li, W Lu, DS Hui, PK Chan, FKL Chan, and SC Ng, Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome. Gut, 03, 2022. 71(3): p. 544-552. DOI: https://doi.org/10.1136/gutjnl-2021-325989
L Zhang, Z Xu, JWY Mak, KM Chow, G Lui, TCM Li, CK Wong, PKS Chan, JYL Ching, Y Fujiwara, FKL Chan, and SC Ng, Gut microbiota-derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID-19: An open-label pilot study. Journal of Gastroenterology and Hepatology, 03, 2022. (Online First). DOI: https://doi.org/10.1111/jgh.15796
SC Ng, Y Peng, L Zhang, CK Mok, S Zhao, A Li, JY Ching, Y Liu, S Yan, DLS Chan, J Zhu, C Chen, AC Fung, KK Wong, DS Hui, FK Chan, and HM Tun, Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events. Gut, 02, 2022. DOI: https://doi.org/10.1136/gutjnl-2021-326563
YK Yau, WYJ Mak, NSR Lui, WYR Ng, CYK Cheung, YLA Li, YLJ Ching, ML Chin, HSL Lau, KLF Chan, KSP Chan, and SC Ng, High prevalence of extended-spectrum beta-lactamase organisms and the COVID-19 pandemic impact on donor recruitment for fecal microbiota transplantation in Hong Kong. United European Gastroenterology Journal, 11, 2021. 9(9): p. 1027-1038. DOI: https://doi.org/10.1002/ueg2.12160
F Zhang, Y Wan, T Zuo, YK Yeoh, Q Liu, L Zhang, H Zhan, W Lu, W Xu, GCY Lui, AYL Li, CP Cheung, CK Wong, PKS Chan, FKL Chan, and SC Ng, Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19. Gastroenterology, 10, 2021. DOI: https://doi.org/10.1053/j.gastro.2021.10.013
MF Neurath, K Uberla, and SC Ng, Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19. Gut, 09, 2021. 70(9): p. 1605-1608. DOI: https://doi.org/10.1136/gutjnl-2021-324622
YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li, ACK Chung, CP Cheung, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, KM Chow, SSS Ng, TCM Li, RWY Ng, TCF Yip, GLH Wong, FKL Chan, CK Wong, PKS Chan, and SC Ng, Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19. Gut, 04, 2021. 70(4): p. 698-706. DOI: https://doi.org/10.1136/gutjnl-2020-323020
T Zuo, Q Liu, F Zhang, YK Yeoh, YT Wan, H Zhan, GCY Lui, ZG Chen, AYL Li, CP Cheung, N Chen, WQ Lv, RWY Ng, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity. Microbiome, 04, 2021. 9(1): p. 16. DOI: https://doi.org/10.1186/s40168-021-01008-x
JL Hu, L Zhang, W Lin, W Tang, FKL Chan, and SC Ng, Review article: Probiotics, prebiotics and dietary approaches during COVID-19 pandemic. Trends in Food Science & Technology, 02, 2021. 108: p. 187-196. DOI: https://doi.org/10.1016/j.tifs.2020.12.009
T Zuo, Q Liu, F Zhang, GCY Lui, EYK Tso, YK Yeoh, ZG Chen, SS Boon, FKL Chan, PKS Chan, and SC Ng, Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19. Gut, 02, 2021. 70(2): p. 276-284. DOI: https://doi.org/10.1136/gutjnl-2020-322294
SC Ng, JWY Mak, L Hitz, Y Chowers, CN Bernstein, and MS Silverberg, COVID-19 Pandemic: Which IBD Patients Need to Be Scoped-Who Gets Scoped Now, Who Can Wait, and how to Resume to Normal. Journal of Crohn's & Colitis, 10, 2020. 14(Supplement_3): p. S791-s797. DOI: https://doi.org/10.1093/ecco-jcc/jjaa128
JWY Mak, MT Weng, SC Wei, and SC Ng, Zero COVID-19 infection in inflammatory bowel disease patients: Findings from population-based inflammatory bowel disease registries in Hong Kong and Taiwan. Journal of Gastroenterology and Hepatology, 06, 2020. DOI: https://doi.org/10.1111/jgh.15164
SC Ng and H Tilg, COVID-19 and the gastrointestinal tract: more than meets the eye. Gut, 06, 2020. 69(6): p. 973-974. DOI: https://doi.org/10.1136/gutjnl-2020-321195
T Zuo, H Zhan, F Zhang, Q Liu, EYK Tso, GCY Lui, N Chen, A Li, W Lu, FKL Chan, PKS Chan, and SC Ng, Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge. Gastroenterology, 06, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.06.048
T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan, Y Wan, A Chung, CP Cheung, N Chen, CKC Lai, Z Chen, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization. Gastroenterology, 05, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.05.048
PWY Chiu, SC Ng, H Inoue, DN Reddy, E Ling Hu, JY Cho, LK Ho, DG Hewett, HM Chiu, R Rerknimitr, HP Wang, SH Ho, DW Seo, KL Goh, H Tajiri, S Kitano, and FKL Chan, Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements). Gut, 04, 2020. DOI: https://doi.org/10.1136/gutjnl-2020-321185
JWY Mak, FKL Chan, and SC Ng, Probiotics and COVID-19: one size does not fit all. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30122-9
SC Ng, FKL Chan, and PKS Chan, Screening FMT donors during the COVID-19 pandemic: a protocol for stool SARS-CoV-2 viral quantification. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30124-2
YK Yau, LH Shing Lau, RN Shun Lui, SH Wong, CL Guo, JW Yan Mak, JY Ling Ching, M Ip, MA Kamm, DT Rubin, PK Sheung Chan, FK Leung Chan, and SC Ng, Long-Term Safety Outcomes of Fecal Microbiota Transplantation: Real-World Data Over 8 Years From the Hong Kong FMT Registry. Clinical Gastroenterology and Hepatology, Sep 19, 2023. DOI: https://doi.org/10.1016/j.cgh.2023.09.001
YK Yau, Q Su, Z Xu, W Tang, JYL Ching, JWY Mak, CP Cheung, M Fung, M Ip, PKS Chan, JCY Wu, FKL Chan, and SC Ng, Randomised clinical trial: Faecal microbiota transplantation for irritable bowel syndrome with diarrhoea. Alimentary Pharmacology & Therapeutics, Oct, 2023. 58(8): p. 795-804. DOI: https://doi.org/10.1111/apt.17703
Q Liu, Z Xu, M Dai, Q Su, FK Leung Chan, and SC Ng, Faecal microbiota transplantations and the role of bacteriophages. Clinical Microbiology and Infection, 06, 2023. 29(6): p. 689-694. DOI: https://doi.org/10.1016/j.cmi.2022.11.012
ZL Xu, JWY Mak, Y Lin, KL Yang, Q Liu, F Zhang, L Lau, WT Tang, JYL Ching, HM Tun, PL Chan, FKL Chan, and SC Ng, Mixed-donor faecal microbiota transplantation was associated with increased butyrate-producing bacteria for obesity. Gut, 03, 2023. DOI: https://doi.org/10.1136/gutjnl-2022-328993
Q Liu, T Zuo, WQ Lu, Y Yeoh, Q Su, ZL Xu, N Tang, KL Yang, F Zhang, LHS Lau, RNS Lui, ML Chin, R Wong, CP Cheung, WY Zhu, P Chan, RC Chan, GC Lui, and SC Ng, Longitudinal Evaluation of Gut Bacteriomes and Viromes after Fecal Microbiota Transplantation for Eradication of Carbapenem-Resistant Enterobacteriaceae. Msystems, 06, 2022: p. 16. DOI: https://doi.org/10.1128/msystems.01510-21
YK Yau, WYJ Mak, NSR Lui, WYR Ng, CYK Cheung, YLA Li, YLJ Ching, ML Chin, HSL Lau, KLF Chan, KSP Chan, and SC Ng, High prevalence of extended-spectrum beta-lactamase organisms and the COVID-19 pandemic impact on donor recruitment for fecal microbiota transplantation in Hong Kong. United European Gastroenterology Journal, 11, 2021. 9(9): p. 1027-1038. DOI: https://doi.org/10.1002/ueg2.12160
F Zhang, T Zuo, YK Yeoh, FWT Cheng, Q Liu, W Tang, KCY Cheung, KL Yang, CP Cheung, CC Mo, MM Hui, FKL Chan, CK Li, PKS Chan, and SC Ng, Longitudinal dynamics of gut bacteriome, mycobiome and virome after fecal microbiota transplantation in graft-versus-host disease. Nature Communications, 01, 2021. 12(1): p. 11. DOI: https://doi.org/10.1038/s41467-020-20240-x
JHS You, X Jiang, WH Lee, PKS Chan, and SC Ng, Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection in patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology, 02, 2020. DOI: https://doi.org/10.1111/jgh.15002
SC Ng, MA Kamm, YK Yeoh, PKS Chan, T Zuo, W Tang, A Sood, A Andoh, N Ohmiya, Y Zhou, CJ Ooi, V Mahachai, CY Wu, F Zhang, K Sugano, and FKL Chan, Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE). Gut, 01, 2020. 69(1): p. 83-91. DOI: https://doi.org/10.1136/gutjnl-2019-319407
RN Lui, SH Wong, LHS Lau, TT Chan, KCY Cheung, A Li, ML Chin, W Tang, JYL Ching, KLY Lam, PKS Chan, JCY Wu, JJY Sung, FKL Chan, and SC Ng, Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong. Hong Kong Medical Journal, 06, 2019. 25(3): p. 178-182. DOI: https://doi.org/10.12809/hkmj197855
CY Lai, J Sung, F Cheng, W Tang, SH Wong, PKS Chan, MA Kamm, JJY Sung, G Kaplan, FKL Chan, and SC Ng, Systematic review with meta-analysis: review of donor features, procedures and outcomes in 168 clinical studies of faecal microbiota transplantation. Alimentary Pharmacology and Therapeutics, 02, 2019. 49(4): p. 354-363. DOI: https://doi.org/10.1111/apt.15116
T Zuo, SH Wong, CP Cheung, K Lam, R Lui, K Cheung, F Zhang, W Tang, JYL Ching, JCY Wu, PKS Chan, JJY Sung, J Yu, FKL Chan, and SC Ng, Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection. Nature Communications, 09, 2018. 9(1): p. 3663. DOI: https://doi.org/10.1038/s41467-018-06103-6
T Zuo, SH Wong, K Lam, R Lui, K Cheung, W Tang, JYL Ching, PKS Chan, MCW Chan, JCY Wu, FKL Chan, J Yu, JJY Sung, and SC Ng, Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome. Gut, 04, 2017. 67(4): p. 634-643. DOI: https://doi.org/10.1136/gutjnl-2017-313952
JY Zheng, QR Sun, JW Zhang, and SC Ng, The role of gut microbiome in inflammatory bowel disease diagnosis and prognosis. United European Gastroenterology Journal, 12, 2022. 10(10): p. 1091-1102. DOI: https://doi.org/10.1002/ueg2.12338
JWY Mak, S Yang, A Stanley, XQ Lin, M Morrison, JYL Ching, JK Niu, AL Wilson-O'Brien, R Feng, W Tang, AL Hamilton, L Or, GL Trakman, WYY Lin, JJY Sung, MH Chen, YL Mao, MA Kamm, and SC Ng, Childhood antibiotics as a risk factor for Crohn's disease: The ENIGMA International Cohort Study. Jgh Open, 06, 2022. 6(6): p. 369-377. DOI: https://doi.org/10.1002/jgh3.12755
SM Lin, LH Lau, N Chanchlani, NA Kennedy, and SC Ng, Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic. Gut, 04, 2022: p. 14. DOI: https://doi.org/10.1136/gutjnl-2021-326784
X Zhilu, D Xiangqian, Y Keli, C Caroline, Z Jingwan, L Yu, Z Tao, CL Cheung, S Yang, Z Fengrui, CF Kl, SJ Jy, Y Jun, B Anthony, B Nicolas, C Jean-Frederic, WS Hei, M Yinglei, and CN Siew, Association of Adherent-invasive Escherichia coli with severe Gut Mucosal dysbiosis in Hong Kong Chinese population with Crohn's disease. Gut Microbes, 11, 2021. 13(1). DOI: https://doi.org/10.1080/19490976.2021.1994833
J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh, A Hamilton, OB AW, JYL Ching, H Wei, K Yang, Z Xu, SH Wong, JWY Mak, JJY Sung, M Morrison, J Yu, MA Kamm, and SC Ng, Elucidation of Proteus mirabilis as a Key Bacterium in Crohn's Disease Inflammation. Gastroenterology, 01, 2021. 160(1): p. 317-330.e11. DOI: https://doi.org/10.1053/j.gastro.2020.09.036
JWY Mak, MT Weng, SC Wei, and SC Ng, Zero COVID-19 infection in inflammatory bowel disease patients: Findings from population-based inflammatory bowel disease registries in Hong Kong and Taiwan. Journal of Gastroenterology and Hepatology, 06, 2020. DOI: https://doi.org/10.1111/jgh.15164
JHS You, X Jiang, WH Lee, PKS Chan, and SC Ng, Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection in patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology, 02, 2020. DOI: https://doi.org/10.1111/jgh.15002
S Lam, T Zuo, M Ho, FKL Chan, PKS Chan, and SC Ng, Review article: fungal alterations in inflammatory bowel diseases. Alimentary Pharmacology and Therapeutics, 12, 2019. 50(11-12): p. 1159-1171. DOI: https://doi.org/10.1111/apt.15523
T Zuo, XJ Lu, Y Zhang, CP Cheung, S Lam, F Zhang, W Tang, JYL Ching, R Zhao, PKS Chan, JJY Sung, J Yu, FKL Chan, Q Cao, JQ Sheng, and SC Ng, Gut mucosal virome alterations in ulcerative colitis. Gut, 07, 2019. 68(7): p. 1169-1179. DOI: https://doi.org/10.1136/gutjnl-2018-318131
T Zuo and SC Ng, Authors response: giant oversights in the human gut virome. Gut, 07, 2019. DOI: https://doi.org/10.1136/gutjnl-2019-319357
T Zuo and SC Ng, The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease. Frontiers in Microbiology, 09, 2018. 9: p. 2247. DOI: https://doi.org/10.3389/fmicb.2018.02247
T Zuo, MA Kamm, JF Colombel, and SC Ng, Urbanization and the gut microbiota in health and inflammatory bowel disease. Nature Reviews Gastroenterology & Hepatology, 07, 2018. 15(7): p. 440-452. DOI: https://doi.org/10.1038/s41575-018-0003-z
SC Ng, JL Benjamin, NE McCarthy, CRH Hedin, A Koutsoumpas, S Plamondon, CL Price, AL Hart, MA Kamm, A Forbes, SC Knight, JO Lindsay, K Whelan, and AJ Stagg, Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflammatory Bowel Diseases, 10, 2011. 17(10): p. 2027-2037. DOI: https://doi.org/10.1002/ibd.21590
SC Ng, MA Kamm, J Stagg, and SC Knight, Intestinal Dendritic Cells: Their Role in Bacterial Recognition, Lymphocyte Homing, and Intestinal Inflammation. Inflammatory Bowel Diseases, 10, 2010. 16(10): p. 1787-1807. DOI: https://doi.org/10.1002/ibd.21247
SC Ng, S Plamondon, MA Kamm, AL Hart, HO Al-Hassi, T Guenther, AJ Stagg, and SC Knight, Immunosuppressive effects via human intestinal dendritic cells of probiotic bacteria and steroids in the treatment of acute ulcerative colitis. Inflammatory Bowel Diseases, 08, 2010. 16(8): p. 1286-98. DOI: https://doi.org/10.1002/ibd.21222
SC Ng, AL Hart, MA Kamm, AJ Stagg, and SC Knight, Mechanisms of action of probiotics: Recent advances. Inflammatory Bowel Diseases, 02, 2009. 15(2): p. 300-310. DOI: https://doi.org/10.1002/ibd.20602
Y Wan, T Zuo, Z Xu, F Zhang, H Zhan, D Chan, TF Leung, YK Yeoh, FKL Chan, R Chan, and SC Ng, Underdevelopment of the gut microbiota and bacteria species as non-invasive markers of prediction in children with autism spectrum disorder. Gut, 07, 2021. DOI: https://doi.org/10.1136/gutjnl-2020-324015
FKL Chan, MCS Wong, AT Chan, JE East, HM Chiu, GK Makharia, D Weller, CJ Ooi, J Limsrivilai, Y Saito, DV Hang, JD Emery, D Makmun, KC Wu, RAR Ali, and SC Ng, Joint Asian Pacific Association of Gastroenterology (APAGE)-Asian Pacific Society of Digestive Endoscopy (APSDE) clinical practice guidelines on the use of non-invasive biomarkers for diagnosis of colorectal neoplasia. Gut, 04, 2023: p. 15. DOI: https://doi.org/10.1136/gutjnl-2023-329429
JQ Liang, Y Zeng, EYT Lau, Y Sun, Y Huang, T Zhou, Z Xu, J Yu, SC Ng, and FKL Chan, A Probiotic Formula for Modulation of Colorectal Cancer Risk via Reducing CRC-Associated Bacteria. Cells, 04, 2023. 12(9). DOI: https://doi.org/10.3390/cells12091244
M Iwatate, D Hirata, CPD Francisco, JT Co, JS Byeon, N Joshi, R Banerjee, DT Quach, TT Aye, HM Chiu, LH Louis, SC Ng, TL Ang, S Khomvilai, XB Li, SH Ho, W Sano, S Hattori, M Fujita, Y Murakami, M Shimatani, Y Kodama, and Y Sano, Efficacy of international web-based educational intervention in the detection of high-risk flat and depressed colorectal lesions higher (CATCH project) with a video: A randomized trial. Digestive Endoscopy, 02, 2022. DOI: https://doi.org/10.1111/den.14244
C Foppa, SC Ng, M Montorsi, and A Spinelli, Anastomotic leak in colorectal cancer patients: New insights and perspectives. European Journal of Oncology, 02, 2020. DOI: https://doi.org/10.1016/j.ejso.2020.02.027
SC Ng, MH Kyaw, BY Suen, YK Tse, MCS Wong, AJ Hui, HY Tak, JYW Lau, JJY Sung, and FKL Chan, Prospective colonoscopic study to investigate risk of colorectal neoplasms in first-degree relatives of patients with non-advanced adenomas. Gut, 04, 2019. DOI: https://doi.org/10.1136/gutjnl-2018-318117
HW Hirai, JYL Ching, JCY Wu, JJY Sung, FKL Chan, and SC Ng, Risk factors for advanced colorectal neoplasms in the proximal colon in 6218 subjects undergoing complete colonoscopy. Journal of Gastroenterology and Hepatology, 01, 2018. 34(1): p. 113-119. DOI: https://doi.org/10.1111/jgh.14357
MCS Wong, JYL Ching, HM Chiu, KC Wu, R Rerknimitr, J Li, DC Wu, KL Goh, T Matsuda, HS Kim, R Leong, KG Yeoh, VH Chong, JD Sollano, F Ahmed, J Menon, SC Ng, JCY Wu, FKL Chan, and JJY Sung, Risk of Colorectal Neoplasia in Individuals with Self-Reported Family History: A Prospective Colonoscopy Study from 16 Asia-Pacific Regions. American Journal of Gastroenterology, 11, 2016. 111(11): p. 1621-1629. DOI: https://doi.org/10.1038/ajg.2016.52
MC Wong, JY Ching, VC Chan, RS Tang, AK Luk, TY Lam, SS Wong, SC Ng, SS Ng, JC Wu, FK Chan, and JJ Sung, Validation of a risk prediction score for proximal neoplasia in colorectal cancer screening: a prospective colonoscopy study. Scientific Reports, 08, 2016. 6: p. 20396. DOI: https://doi.org/10.1038/srep20396
HW Hirai, KKF Tsoi, JYC Chan, SH Wong, JYL Ching, MCS Wong, JCY Wu, FKL Chan, JJY Sung, and SC Ng, Systematic review with meta-analysis: Faecal occult blood tests show lower colorectal cancer detection rates in the proximal colon in colonoscopy-verified diagnostic studies. Alimentary Pharmacology and Therapeutics, 04, 2016. 43(7): p. 755-764. DOI: https://doi.org/10.1111/apt.13556
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SH Wong, SC Ng, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Colorectal cancer screening based on age and gender: A cost-effectiveness analysis. Medicine, 03, 2016. 95(10): p. e2739. DOI: https://doi.org/10.1097/MD.0000000000002739
MC Wong, JY Ching, S Ng, TY Lam, AK Luk, SH Wong, SC Ng, SS Ng, JC Wu, FK Chan, and JJ Sung, The discriminatory capability of existing scores to predict advanced colorectal neoplasia: a prospective colonoscopy study of 5,899 screening participants. Scientific Reports, 02, 2016. 6: p. 20080. DOI: https://doi.org/10.1038/srep20080
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SH Wong, SC Ng, VWS Wong, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Screening strategies for colorectal cancer among patients with nonalcoholic fatty liver disease and family history. International Journal of Cancer, 02, 2016. 138: p. 576-583. DOI: https://doi.org/10.1002/ijc.29809
MCS Wong, SH Wong, SC Ng, JCY Wu, FKL Chan, and JJY Sung, Targeted screening for colorectal cancer in high-risk individuals. Best Practice & Research Clinical Gastroenterology, 12, 2015. 29(6): p. 941-951. DOI: https://doi.org/10.1016/j.bpg.2015.09.006
Q Gao, KKF Tsoi, HW Hirai, MCS Wong, FKL Chan, JCY Wu, JYW Lau, JJY Sung, and SC Ng, Serrated polyps and the risk of synchronous colorectal advanced neoplasia: A systematic review and meta-analysis. American Journal of Gastroenterology, 04, 2015. 110(4): p. 501-509. DOI: https://doi.org/10.1038/ajg.2015.49
SC Ng, JYL Ching, VCW Chan, MCS Wong, R Tang, S Wong, AKC Luk, TYT Lam, Q Gao, AWH Chan, JCY Wu, FKL Chan, JYW Lau, and JJY Sung, Association between serrated polyps and the risk of synchronous advanced colorectal neoplasia in average-risk individuals. Alimentary Pharmacology and Therapeutics, 01, 2015. 41(1): p. 108-115. DOI: https://doi.org/10.1111/apt.13003
JJY Sung, SC Ng, FKL Chan, HM Chiu, HS Kim, T Matsuda, SSM Ng, JYW Lau, S Zheng, S Adler, N Reddy, KG Yeoh, KKF Tsoi, JYL Ching, EJ Kuipers, L Rabeneck, GP Young, RJ Steele, D Lieberman, and KL Goh, An updated Asia Pacific Consensus Recommendations on colorectal cancer screening. Gut, 01, 2015. 64(1): p. 121-132. DOI: https://doi.org/10.1136/gutjnl-2013-306503
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SH Wong, SC Ng, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Identification of subjects at risk of proximal advanced neoplasia for colorectal cancer screening. European Journal of Cancer, 01, 2015. 51: p. 37-44. DOI: https://doi.org/10.1016/j.ejca.2014.10.003
MCS Wong, JYL Ching, VCW Chan, TYT Lam, AKC Luk, SC Ng, SSM Ng, and JJY Sung, Informed choice vs. no choice in colorectal cancer screening tests: A prospective cohort study in real-life screening practice. American Journal of Gastroenterology, 07, 2014. 109(7): p. 1072-1079. DOI: https://doi.org/10.1038/ajg.2014.136
CW Wu, SC Ng, Y Dong, L Tian, SSM Ng, WW Leung, WT Law, TO Yau, FKL Chan, JJY Sung, and J Yu, Identification of microrna-135b in stool as a potential noninvasive biomarker for colorectal cancer and adenoma. Clinical Cancer Research, 06, 2014. 20: p. 2994-3002. DOI: https://doi.org/10.1158/1078-0432.CCR-13-1750
SC Ng, JYL Ching, V Chan, MCS Wong, BY Suen, HW Hirai, TYT Lam, WL J.Y, SSM Ng, JCY Wu, FKL Chan, and JJY Sung, Diagnostic accuracy of faecal immunochemical test for screening individuals with a family history of colorectal cancer. Alimentary Pharmacology and Therapeutics, 10, 2013. 38(7): p. 835-841. DOI: https://doi.org/10.1111/apt.12446
SC Ng, JYW Lau, FKL Chan, BY Suen, WK Leung, YK Tse, SSM Ng, JFY Lee, KF To, JCY Wu, and JJY Sung, Increased risk of advanced neoplasms among asymptomatic siblings of patients with colorectal cancer. Gastroenterology, 03, 2013. 144(3): p. 544-550. DOI: https://doi.org/10.1053/j.gastro.2012.11.011
SC Ng and SH Wong, Colorectal cancer screening in Asia. British Medical Bulletin, 03, 2013. 105: p. 29-42. DOI: https://doi.org/10.1093/bmb/lds040
CW Wu, SS Ng, YJ Dong, SC Ng, WW Leung, CW Lee, YN Wong, FK Chan, J Yu, and JJ Sung, Detection of miR-92a and miR-21 in stool samples as potential screening biomarkers for colorectal cancer and polyps. Gut, 05, 2012. 61(5): p. 739-45. DOI: https://doi.org/10.1136/gut.2011.239236
Y Wan, T Zuo, Z Xu, F Zhang, H Zhan, D Chan, TF Leung, YK Yeoh, FKL Chan, R Chan, and SC Ng, Underdevelopment of the gut microbiota and bacteria species as non-invasive markers of prediction in children with autism spectrum disorder. Gut, 07, 2021. DOI: https://doi.org/10.1136/gutjnl-2020-324015
SC Ng, FKL Chan, and PKS Chan, Screening FMT donors during the COVID-19 pandemic: a protocol for stool SARS-CoV-2 viral quantification. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30124-2
JWY Mak, FKL Chan, and SC Ng, Probiotics and COVID-19: one size does not fit all. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30122-9
PWY Chiu, SC Ng, H Inoue, DN Reddy, E Ling Hu, JY Cho, LK Ho, DG Hewett, HM Chiu, R Rerknimitr, HP Wang, SH Ho, DW Seo, KL Goh, H Tajiri, S Kitano, and FKL Chan, Practice of endoscopy during COVID-19 pandemic: position statements of the Asian Pacific Society for Digestive Endoscopy (APSDE-COVID statements). Gut, 04, 2020. DOI: https://doi.org/10.1136/gutjnl-2020-321185
T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan, Y Wan, A Chung, CP Cheung, N Chen, CKC Lai, Z Chen, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization. Gastroenterology, 05, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.05.048
T Zuo, H Zhan, F Zhang, Q Liu, EYK Tso, GCY Lui, N Chen, A Li, W Lu, FKL Chan, PKS Chan, and SC Ng, Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge. Gastroenterology, 06, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.06.048
SC Ng and H Tilg, COVID-19 and the gastrointestinal tract: more than meets the eye. Gut, 06, 2020. 69(6): p. 973-974. DOI: https://doi.org/10.1136/gutjnl-2020-321195
JWY Mak, MT Weng, SC Wei, and SC Ng, Zero COVID-19 infection in inflammatory bowel disease patients: Findings from population-based inflammatory bowel disease registries in Hong Kong and Taiwan. Journal of Gastroenterology and Hepatology, 06, 2020. DOI: https://doi.org/10.1111/jgh.15164
SC Ng, JWY Mak, L Hitz, Y Chowers, CN Bernstein, and MS Silverberg, COVID-19 Pandemic: Which IBD Patients Need to Be Scoped-Who Gets Scoped Now, Who Can Wait, and how to Resume to Normal. Journal of Crohn's & Colitis, 10, 2020. 14(Supplement_3): p. S791-s797. DOI: https://doi.org/10.1093/ecco-jcc/jjaa128
T Zuo, Q Liu, F Zhang, GCY Lui, EYK Tso, YK Yeoh, ZG Chen, SS Boon, FKL Chan, PKS Chan, and SC Ng, Depicting SARS-CoV-2 faecal viral activity in association with gut microbiota composition in patients with COVID-19. Gut, 02, 2021. 70(2): p. 276-284. DOI: https://doi.org/10.1136/gutjnl-2020-322294
JL Hu, L Zhang, W Lin, W Tang, FKL Chan, and SC Ng, Review article: Probiotics, prebiotics and dietary approaches during COVID-19 pandemic. Trends in Food Science & Technology, 02, 2021. 108: p. 187-196. DOI: https://doi.org/10.1016/j.tifs.2020.12.009
T Zuo, Q Liu, F Zhang, YK Yeoh, YT Wan, H Zhan, GCY Lui, ZG Chen, AYL Li, CP Cheung, N Chen, WQ Lv, RWY Ng, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Temporal landscape of human gut RNA and DNA virome in SARS-CoV-2 infection and severity. Microbiome, 04, 2021. 9(1): p. 16. DOI: https://doi.org/10.1186/s40168-021-01008-x
YK Yeoh, T Zuo, GCY Lui, F Zhang, Q Liu, AYL Li, ACK Chung, CP Cheung, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, KM Chow, SSS Ng, TCM Li, RWY Ng, TCF Yip, GLH Wong, FKL Chan, CK Wong, PKS Chan, and SC Ng, Gut microbiota composition reflects disease severity and dysfunctional immune responses in patients with COVID-19. Gut, 04, 2021. 70(4): p. 698-706. DOI: https://doi.org/10.1136/gutjnl-2020-323020
MF Neurath, K Uberla, and SC Ng, Gut as viral reservoir: lessons from gut viromes, HIV and COVID-19. Gut, 09, 2021. 70(9): p. 1605-1608. DOI: https://doi.org/10.1136/gutjnl-2021-324622
F Zhang, Y Wan, T Zuo, YK Yeoh, Q Liu, L Zhang, H Zhan, W Lu, W Xu, GCY Lui, AYL Li, CP Cheung, CK Wong, PKS Chan, FKL Chan, and SC Ng, Prolonged Impairment of Short-Chain Fatty Acid and L-Isoleucine Biosynthesis in Gut Microbiome in Patients With COVID-19. Gastroenterology, 10, 2021. DOI: https://doi.org/10.1053/j.gastro.2021.10.013
YK Yau, WYJ Mak, NSR Lui, WYR Ng, CYK Cheung, YLA Li, YLJ Ching, ML Chin, HSL Lau, KLF Chan, KSP Chan, and SC Ng, High prevalence of extended-spectrum beta-lactamase organisms and the COVID-19 pandemic impact on donor recruitment for fecal microbiota transplantation in Hong Kong. United European Gastroenterology Journal, 11, 2021. 9(9): p. 1027-1038. DOI: https://doi.org/10.1002/ueg2.12160
SC Ng, Y Peng, L Zhang, CK Mok, S Zhao, A Li, JY Ching, Y Liu, S Yan, DLS Chan, J Zhu, C Chen, AC Fung, KK Wong, DS Hui, FK Chan, and HM Tun, Gut microbiota composition is associated with SARS-CoV-2 vaccine immunogenicity and adverse events. Gut, 02, 2022. DOI: https://doi.org/10.1136/gutjnl-2021-326563
L Zhang, Z Xu, JWY Mak, KM Chow, G Lui, TCM Li, CK Wong, PKS Chan, JYL Ching, Y Fujiwara, FKL Chan, and SC Ng, Gut microbiota-derived synbiotic formula (SIM01) as a novel adjuvant therapy for COVID-19: An open-label pilot study. Journal of Gastroenterology and Hepatology, 03, 2022. (Online First). DOI: https://doi.org/10.1111/jgh.15796
Q Liu, JWY Mak, Q Su, YK Yeoh, GC Lui, SSS Ng, F Zhang, AYL Li, W Lu, DS Hui, PK Chan, FKL Chan, and SC Ng, Gut microbiota dynamics in a prospective cohort of patients with post-acute COVID-19 syndrome. Gut, 03, 2022. 71(3): p. 544-552. DOI: https://doi.org/10.1136/gutjnl-2021-325989
SM Lin, LH Lau, N Chanchlani, NA Kennedy, and SC Ng, Recent advances in clinical practice: management of inflammatory bowel disease during the COVID-19 pandemic. Gut, 04, 2022: p. 14. DOI: https://doi.org/10.1136/gutjnl-2021-326784
Q Su, RI Lau, Q Liu, FKL Chan, and SC Ng, Post-acute COVID-19 syndrome and gut dysbiosis linger beyond 1 year after SARS-CoV-2 clearance. Gut, 08, 2022: p. 2. DOI: https://doi.org/10.1136/gutjnl-2022-328319
RI Lau, F Zhang, Q Liu, Q Su, FKL Chan, and SC Ng, Gut microbiota in COVID-19: key microbial changes, potential mechanisms and clinical applications. Nature Reviews Gastroenterology & Hepatology, 10, 2022: p. 15. DOI: https://doi.org/10.1038/s41575-022-00698-4
Q Su, Q Liu, RI Lau, JW Zhang, ZL Xu, YK Yeoh, TWH Leung, W Tang, L Zhang, JQY Liang, YK Yau, JY Zheng, CY Liu, MJ Zhang, CP Cheung, JYL Ching, HM Tun, J Yu, FKL Chan, and SC Ng, Faecal microbiome-based machine learning for multi-class disease diagnosis. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34405-3
Q Liu, Q Su, F Zhang, HM Tun, JWY Mak, GCY Lui, SSS Ng, JYL Ching, A Li, WQ Lu, CY Liu, CP Cheung, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34535-8
Q Su, Q Liu, L Zhang, ZL Xu, CY Liu, WQ Lu, JYL Ching, A Li, JWY Mak, GCY Lui, SSS Ng, KM Chow, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Antibiotics and probiotics impact gut antimicrobial resistance gene reservoir in COVID-19 patients. Gut Microbes, 12, 2022. 14(1): p. 16. DOI: https://doi.org/10.1080/19490976.2022.2128603
SC Ng, AL Hart, MA Kamm, AJ Stagg, and SC Knight, Mechanisms of action of probiotics: Recent advances. Inflammatory Bowel Diseases, 02, 2009. 15(2): p. 300-310. DOI: https://doi.org/10.1002/ibd.20602
SC Ng, S Plamondon, MA Kamm, AL Hart, HO Al-Hassi, T Guenther, AJ Stagg, and SC Knight, Immunosuppressive effects via human intestinal dendritic cells of probiotic bacteria and steroids in the treatment of acute ulcerative colitis. Inflammatory Bowel Diseases, 08, 2010. 16(8): p. 1286-98. DOI: https://doi.org/10.1002/ibd.21222
SC Ng, MA Kamm, J Stagg, and SC Knight, Intestinal Dendritic Cells: Their Role in Bacterial Recognition, Lymphocyte Homing, and Intestinal Inflammation. Inflammatory Bowel Diseases, 10, 2010. 16(10): p. 1787-1807. DOI: https://doi.org/10.1002/ibd.21247
SC Ng, JL Benjamin, NE McCarthy, CRH Hedin, A Koutsoumpas, S Plamondon, CL Price, AL Hart, MA Kamm, A Forbes, SC Knight, JO Lindsay, K Whelan, and AJ Stagg, Relationship between human intestinal dendritic cells, gut microbiota, and disease activity in Crohn's disease. Inflammatory Bowel Diseases, 10, 2011. 17(10): p. 2027-2037. DOI: https://doi.org/10.1002/ibd.21590
SC Ng, EFC Lam, TTY Lam, Y Chan, W Law, PCH Tse, MA Kamm, JJY Sung, FKL Chan, and JCY Wu, Effect of probiotic bacteria on the intestinal microbiota in irritable bowel syndrome. Journal of Gastroenterology and Hepatology, 10, 2013. 28(10): p. 1624-1631. DOI: https://doi.org/10.1111/jgh.12306
G Nakatsu, X Li, H Zhou, J Sheng, SH Wong, WKK Wu, SC Ng, H Tsoi, Y Dong, N Zhang, Y He, Q Kang, L Cao, K Wang, J Zhang, Q Liang, J Yu, and JJY Sung, Gut mucosal microbiome across stages of colorectal carcinogenesis. Nature Communications, 10, 2015. 6: p. 8727. DOI: https://doi.org/10.1038/ncomms9727
SH Wong, TN Kwong, TC Chow, AK Luk, RZ Dai, G Nakatsu, TY Lam, L Zhang, JC Wu, FK Chan, SS Ng, MC Wong, SC Ng, WK Wu, J Yu, and JJ Sung, Quantitation of faecal Fusobacterium improves faecal immunochemical test in detecting advanced colorectal neoplasia. Gut, 10, 2016. 66(8): p. 1441-1448. DOI: https://doi.org/10.1136/gutjnl-2016-312766
J Yu, Q Feng, SH Wong, D Zhang, QY Liang, Y Qin, L Tang, H Zhao, J Stenvang, Y Li, X Wang, X Xu, N Chen, WK Wu, J Al-Aama, HJ Nielsen, P Kiilerich, BA Jensen, TO Yau, Z Lan, H Jia, J Li, L Xiao, TY Lam, SC Ng, AS Cheng, VW Wong, FK Chan, H Yang, L Madsen, C Datz, H Tilg, J Wang, N Brunner, K Kristiansen, M Arumugam, and JJ Sung, Metagenomic analysis of faecal microbiome as a tool towards targeted non-invasive biomarkers for colorectal cancer. Gut, 01, 2017. 66(1): p. 70-78. DOI: https://doi.org/10.1136/gutjnl-2015-309800
T Zuo, SH Wong, K Lam, R Lui, K Cheung, W Tang, JYL Ching, PKS Chan, MCW Chan, JCY Wu, FKL Chan, J Yu, JJY Sung, and SC Ng, Bacteriophage transfer during faecal microbiota transplantation in Clostridium difficile infection is associated with treatment outcome. Gut, 04, 2017. 67(4): p. 634-643. DOI: https://doi.org/10.1136/gutjnl-2017-313952 10.1136/gutjnl-2017-313952.
Q Liang, J Chiu, Y Chen, Y Huang, A Higashimori, J Fang, H Brim, H Ashktorab, SC Ng, SSM Ng, S Zheng, FKL Chan, JJY Sung, and J Yu, Fecal Bacteria Act as Novel Biomarkers for Noninvasive Diagnosis of Colorectal Cancer. Clinical Cancer Research, 04, 2017. 23: p. 2061-2070. DOI: https://doi.org/10.1158/1078-0432.CCR-16-1599
JKY Hooi, WY Lai, WK Ng, MMY Suen, FE Underwood, D Tanyingoh, P Malfertheiner, DY Graham, VWS Wong, JCY Wu, FKL Chan, JJY Sung, GG Kaplan, and SC Ng, Global Prevalence of Helicobacter pylori Infection: Systematic Review and Meta-analysis. Gastroenterology, 08, 2017. 26: p. 26. DOI: https://doi.org/10.1053/j.gastro.2017.04.022
WK Ng, GG Kaplan, and SC Ng, Prevalence of Helicobacter pylori Infection in Asia: Remembrance of Things Past? Reply. Gastroenterology, 01, 2018. 154(1): p. 258-259. DOI: https://doi.org/10.1053/j.gastro.2017.11.028
T Zuo, MA Kamm, JF Colombel, and SC Ng, Urbanization and the gut microbiota in health and inflammatory bowel disease. Nature Reviews Gastroenterology & Hepatology, 07, 2018. 15(7): p. 440-452. DOI: https://doi.org/10.1038/s41575-018-0003-z
G Nakatsu, H Zhou, WKK Wu, SH Wong, OO Coker, Z Dai, X Li, CH Szeto, N Sugimura, TY Lam, AC Yu, X Wang, Z Chen, MC Wong, SC Ng, MTV Chan, PKS Chan, FKL Chan, JJ Sung, and J Yu, Alterations in Enteric Virome Are Associated With Colorectal Cancer and Survival Outcomes. Gastroenterology, 08, 2018. 155(2): p. 529-541 e5. DOI: https://doi.org/10.1053/j.gastro.2018.04.018
TNY Kwong, X Wang, G Nakatsu, TC Chow, T Tipoe, RZW Dai, KKK Tsoi, MCS Wong, G Tse, MTV Chan, FKL Chan, SC Ng, JCY Wu, WKK Wu, J Yu, JJY Sung, and SH Wong, Association Between Bacteremia From Specific Microbes and Subsequent Diagnosis of Colorectal Cancer. Gastroenterology, 08, 2018. 155(2): p. 383-390 e8. DOI: https://doi.org/10.1053/j.gastro.2018.04.028
T Zuo, SH Wong, CP Cheung, K Lam, R Lui, K Cheung, F Zhang, W Tang, JYL Ching, JCY Wu, PKS Chan, JJY Sung, J Yu, FKL Chan, and SC Ng, Gut fungal dysbiosis correlates with reduced efficacy of fecal microbiota transplantation in Clostridium difficile infection. Nature Communications, 09, 2018. 9(1): p. 3663. DOI: https://doi.org/10.1038/s41467-018-06103-6
T Zuo and SC Ng, The Gut Microbiota in the Pathogenesis and Therapeutics of Inflammatory Bowel Disease. Frontiers in Microbiology, 09, 2018. 9: p. 2247. DOI: https://doi.org/10.3389/fmicb.2018.02247
CY Lai, J Sung, F Cheng, W Tang, SH Wong, PKS Chan, MA Kamm, JJY Sung, G Kaplan, FKL Chan, and SC Ng, Systematic review with meta-analysis: review of donor features, procedures and outcomes in 168 clinical studies of faecal microbiota transplantation. Alimentary Pharmacology and Therapeutics, 02, 2019. 49(4): p. 354-363. DOI: https://doi.org/10.1111/apt.15116
RN Lui, SH Wong, LHS Lau, TT Chan, KCY Cheung, A Li, ML Chin, W Tang, JYL Ching, KLY Lam, PKS Chan, JCY Wu, JJY Sung, FKL Chan, and SC Ng, Faecal microbiota transplantation for treatment of recurrent or refractory Clostridioides difficile infection in Hong Kong. Hong Kong Medical Journal, 06, 2019. 25(3): p. 178-182. DOI: https://doi.org/10.12809/hkmj197855
T Zuo and SC Ng, Authors response: giant oversights in the human gut virome. Gut, 07, 2019. DOI: https://doi.org/10.1136/gutjnl-2019-319357
T Zuo, XJ Lu, Y Zhang, CP Cheung, S Lam, F Zhang, W Tang, JYL Ching, R Zhao, PKS Chan, JJY Sung, J Yu, FKL Chan, Q Cao, JQ Sheng, and SC Ng, Gut mucosal virome alterations in ulcerative colitis. Gut, 07, 2019. 68(7): p. 1169-1179. DOI: https://doi.org/10.1136/gutjnl-2018-318131
JQ Liang, T Li, G Nakatsu, YX Chen, TO Yau, E Chu, S Wong, CH Szeto, SC Ng, FKL Chan, JY Fang, JJY Sung, and J Yu, A novel faecal Lachnoclostridium marker for the non-invasive diagnosis of colorectal adenoma and cancer. Gut, 11, 2019. DOI: https://doi.org/10.1136/gutjnl-2019-318532
S Lam, T Zuo, M Ho, FKL Chan, PKS Chan, and SC Ng, Review article: fungal alterations in inflammatory bowel diseases. Alimentary Pharmacology and Therapeutics, 12, 2019. 50(11-12): p. 1159-1171. DOI: https://doi.org/10.1111/apt.15523
SC Ng, MA Kamm, YK Yeoh, PKS Chan, T Zuo, W Tang, A Sood, A Andoh, N Ohmiya, Y Zhou, CJ Ooi, V Mahachai, CY Wu, F Zhang, K Sugano, and FKL Chan, Scientific frontiers in faecal microbiota transplantation: joint document of Asia-Pacific Association of Gastroenterology (APAGE) and Asia-Pacific Society for Digestive Endoscopy (APSDE). Gut, 01, 2020. 69(1): p. 83-91. DOI: https://doi.org/10.1136/gutjnl-2019-319407
JHS You, X Jiang, WH Lee, PKS Chan, and SC Ng, Cost-effectiveness analysis of fecal microbiota transplantation for recurrent Clostridium difficile infection in patients with inflammatory bowel disease. Journal of Gastroenterology and Hepatology, 02, 2020. DOI: https://doi.org/10.1111/jgh.15002
YK Yeoh, Z Chen, MCS Wong, M Hui, J Yu, SC Ng, JJY Sung, FKL Chan, and PKS Chan, Southern Chinese populations harbour non-nucleatum Fusobacteria possessing homologues of the colorectal cancer-associated FadA virulence factor. Gut, 02, 2020. DOI: https://doi.org/10.1136/gutjnl-2019-319635
SC Ng, FKL Chan, and PKS Chan, Screening FMT donors during the COVID-19 pandemic: a protocol for stool SARS-CoV-2 viral quantification. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30124-2
JWY Mak, FKL Chan, and SC Ng, Probiotics and COVID-19: one size does not fit all. Lancet Gastroenterology & Hepatology, 04, 2020. DOI: https://doi.org/10.1016/S2468-1253(20)30122-9
T Zuo, F Zhang, GCY Lui, YK Yeoh, AYL Li, H Zhan, Y Wan, A Chung, CP Cheung, N Chen, CKC Lai, Z Chen, EYK Tso, KSC Fung, V Chan, L Ling, G Joynt, DSC Hui, FKL Chan, PKS Chan, and SC Ng, Alterations in Gut Microbiota of Patients With COVID-19 During Time of Hospitalization. Gastroenterology, 05, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.05.048
T Zuo, H Zhan, F Zhang, Q Liu, EYK Tso, GCY Lui, N Chen, A Li, W Lu, FKL Chan, PKS Chan, and SC Ng, Alterations in Fecal Fungal Microbiome of Patients With COVID-19 During Time of Hospitalization until Discharge. Gastroenterology, 06, 2020. DOI: https://doi.org/10.1053/j.gastro.2020.06.048
T Zuo, Y Sun, Y Wan, YK Yeoh, F Zhang, CP Cheung, N Chen, J Luo, W Wang, JJY Sung, PKS Chan, K Wang, FKL Chan, Y Miao, and SC Ng, Human-Gut-DNA Virome Variations across Geography, Ethnicity, and Urbanization. Cell Host & Microbe, 11, 2020. 28(5): p. 741-751.e4. DOI: https://doi.org/10.1016/j.chom.2020.08.005
J Zhang, EC Hoedt, Q Liu, E Berendsen, JJ Teh, A Hamilton, OB AW, JYL Ching, H Wei, K Yang, Z Xu, SH Wong, JWY Mak, JJY Sung, M Morrison, J Yu, MA Kamm, and SC Ng, Elucidation of Proteus mirabilis as a Key Bacterium in Crohn's Disease Inflammation. Gastroenterology, 01, 2021. 160(1): p. 317-330.e11. DOI: https://doi.org/10.1053/j.gastro.2020.09.036
F Zhang, T Zuo, YK Yeoh, FWT Cheng, Q Liu, W Tang, KCY Cheung, KL Yang, CP Cheung, CC Mo, MM Hui, FKL Chan, CK Li, PKS Chan, and SC Ng, Longitudinal dynamics of gut bacteriome, mycobiome and virome after fecal microbiota transplantation in graft-versus-host disease. Nature Communications, 01, 2021. 12(1): p. 11. DOI: https://doi.org/10.1038/s41467-020-20240-x
Y Wan, T Zuo, Z Xu, F Zhang, H Zhan, D Chan, TF Leung, YK Yeoh, FKL Chan, R Chan, and SC Ng, Underdevelopment of the gut microbiota and bacteria species as non-invasive markers of prediction in children with autism spectrum disorder. Gut, 07, 2021. DOI: https://doi.org/10.1136/gutjnl-2020-324015
Q Liu, T Zuo, WQ Lu, Y Yeoh, Q Su, ZL Xu, N Tang, KL Yang, F Zhang, LHS Lau, RNS Lui, ML Chin, R Wong, CP Cheung, WY Zhu, P Chan, RC Chan, GC Lui, and SC Ng, Longitudinal Evaluation of Gut Bacteriomes and Viromes after Fecal Microbiota Transplantation for Eradication of Carbapenem-Resistant Enterobacteriaceae. Msystems, 06, 2022: p. 16. DOI: https://doi.org/10.1128/msystems.01510-21
Q Su, Q Liu, RI Lau, JW Zhang, ZL Xu, YK Yeoh, TWH Leung, W Tang, L Zhang, JQY Liang, YK Yau, JY Zheng, CY Liu, MJ Zhang, CP Cheung, JYL Ching, HM Tun, J Yu, FKL Chan, and SC Ng, Faecal microbiome-based machine learning for multi-class disease diagnosis. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34405-3
Q Liu, Q Su, F Zhang, HM Tun, JWY Mak, GCY Lui, SSS Ng, JYL Ching, A Li, WQ Lu, CY Liu, CP Cheung, DSC Hui, PKS Chan, FKL Chan, and SC Ng, Multi-kingdom gut microbiota analyses define COVID-19 severity and post-acute COVID-19 syndrome. Nature Communications, 11, 2022. 13(1). DOI: https://doi.org/10.1038/s41467-022-34535-8
Q Liu, Z Xu, M Dai, Q Su, FK Leung Chan, and SC Ng, Faecal microbiota transplantations and the role of bacteriophages. Clinical Microbiology and Infection, 06, 2023. 29(6): p. 689-694. DOI: https://doi.org/10.1016/j.cmi.2022.11.012